About Dr. Laurie
Keefer

Professor of Medicine, Psychiatry &
Biomedical Sciences | Icahn School of
Medicine at Mount Sinai

Download CV

Global Leader in Gastropsychology

Laurie Keefer, PhD is a world-renowned Clinical Health Psychologist and Professor of
Medicine, Psychiatry, and Biomedical Sciences at the Icahn School of Medicine at
Mount Sinai in New York. She earned her PhD from the University at Albany and completed
her rigorous clinical training at Rush University Medical Center in Chicago.

For over 25 years, Dr. Keefer has dedicated her career to the integration of psychosocial
care into the routine management of chronic digestive diseases. Her pioneering work has
fundamentally changed how inflammatory bowel disease (IBD) and other gastrointestinal
disorders are treated, shifting the focus from symptom management to holistic resilience
and brain-gut health.

"Currently serving as the Director of Psychobehavioral Research at Mount Sinai, Dr. Keefer
continues to push the boundaries of clinical health psychology, mentoring the next generation
of researchers and clinicians while maintaining a patient-centered philosophy that prioritizes
emotional well-being as a cornerstone of physical health."

A Journey of Impact

  • Penn State University

    1997 — FOUNDATION

    Earned dual BA degrees in Psychology and Women's Studies,
    laying the groundwork for a Career focused on service and leadership

  • University at Albany

    Focusing research on the application of behavioral interventions to medical conditions, developed interest in the brain-gut.

  • Rush University Medical Center

    2003 – 2005 — CLINICAL FIRST

    Residency and Fellowship. Became the first integrated health
    psychologist specifically dedicated to GI patients, a role that
    defined a new specialty.

  • Northwestern University

    2006 – 2015 — EXPANSION

    Expanded the role of Gastropsychology, acquired NIH funding, built one of the nation’s premier gastropsychology clinical and research programs

  • Icahn School of Medicine at Mount Sinai

    2016 – PRESENT — LEADERSHIP

    Leads a subspecialty medical home for complex IBD, invented the GRITT Method

Treating the Whole Person

Dr. Keefer's philosophy centers on the belief that a patient's
emotional landscape is inseparable from their physical recovery. By
integrating behavioral medicine into gastrointestinal care, she
focuses on early intervention and building sustainable resilience.

Evidence-based, brain-gut behavior therapies

Integrated care models

Treatment targets include emotional healing

"Effective healthcare begins by
treating the whole person—not
just the disease."

— DR. LAURIE KEEFER

INNOVATION

The GRITT Method

Gaining Resilience Through Transitions (GRITT) is a patent-pending comprehensive framework that leverages risk stratification algorithms and precision behavioral medicine techniques to optimize chronic condition management. Developed and tested at Mount Sinai and licensed to Trellus Health (co-founded by Dr Keefer) for scaling and digitizing.

Risk Stratification

Personalized Care Pathways

Multidisciplinary team communication method

Transforming Care Delivery

GRITT provides a framework for multi-disciplinary teams to communicate effectively while delivering personalized psychological support tailored to the patient's specific health trajectory.

MARKET IMPACT

Now serving thousands through Trellus Health's digital platform, providing 24/7 access to resilience-based care.

PROFESSIONAL LEADERSHIP & HONORS

AFFILIATIONS

Rome Foundation

Chief Executive Officer

Psychogastroenterology

Founder & Chair

American Neurogastroenterology and Motility Society

Former Council Member

Crohn’s and Colitis Foundation

Consultant, Methodology and Impact

"I believe emotional healing
should be treated with the same
urgency and precision as physical healing."